You treat it with recombinant leptin therapy. Basically just give the kid some leptin. Its worked in the past.

So if these children demand inordinate amounts of food, do you treat them by restricting it or by appetite suppressants? Are there ways to treat this deficiency? I guess you are working on it, good researcher that you are.

My ability to do basis science research is very limited: I simply cannot do bench work. Respect the heck out of those of you who can….

im curious what kind of research did you do with leptin deficiency? I forwarded the article to a friend of mine who works for one of the researchers that discovered letpin/leptin receptor and said there are a host of other hormones that can cause such obesity. Hard to tell without any other info.

I did once work on research connected to leptin deficiency though, and based on that, I’ll just comment that kids that have this disorder are unable to control their appetite. So, unless his parents are really doting on him excessively, he may actually be demanding the inordinate amounts of food.

MD is a pathologist and has very little contact with Pediatrics or pediatric pathology and hasn’t a clue unless she does a little cracking open of the books

Hormonal problem? But why is this child taking in so much milk and rice? Wouldn’t any child eating that much a day at that age be, well, zaftig? Those are adult amounts of calories, no? Why are they feeding this child this much? Surely at this age you can control how much he/she eats? I know of syndromes where children eat everything around them, but that doesn’t seem likely……

Dunno, will get back to you.

He’s welcome in Wisconsin any day.

What a cutie! I love fat babies, too.

but then my concern for his health wins out and I panic…